SCHEMBL8344802

SCHEMBL8344802

COC(=N)NC(=O)OC.[Zn]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8196368 0.97
SCHEMBL9137593 0.75 GAA (0.42) ALDH1A1HSD17B10LMNAHPGDALOX15
SCHEMBL11250788 0.75 TSHR (0.39) HPGDTSHR
SCHEMBL862169 0.75
SCHEMBL3074860 0.75
SCHEMBL5440136 0.74
SCHEMBL8509308 0.74
SCHEMBL10817076 0.74
SCHEMBL1820735 0.72
SCHEMBL10331892 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5885935-A Sulfonamide herbicides AGREVO UK LIMITED (GB) 1999-03-23 US disclosed
EP-0625970-B1 SULFONAMIDE HERBICIDES AGREVO UK LTD (GB) 1997-09-17 EP disclosed
US-5559081-A Sulfonamide herbicides AGREVO UK LIMITED (GB) 1996-09-24 US disclosed
EP-0625970-A1 SULFONAMIDE HERBICIDES. AGREVO UK LTD (GB) 1994-11-30 EP disclosed
WO-1993009099-A2 SULFONAMIDE HERBICIDES AGREVO UK LIMITED (GB) 1993-05-13 WO disclosed