Cyclopropane

Cyclopropane

SCHEMBL8344846

C1CC1.O=C(O)c1ccc(C(=O)OCCO)cc1

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 1/20 0.47
LMNA P02545 3/20 0.46
CYP2D6 P10635 2/20 0.45
TSHR P16473 4/20 0.44
ESR1 P03372 3/20 0.44
ALDH1A1 P00352 3/20 0.44
CHRM1 P11229 1/20 0.44
SLC6A2 P23975 1/20 0.44
KDR P35968 1/20 0.44
TP53 P04637 1/20 0.44
ESR2 Q92731 1/20 0.44
RAB9A P51151 3/20 0.42
NPC1 O15118 1/20 0.42
SLC7A5 Q01650 1/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL22501390 1.00 TDP1 (0.48) TDP1MEN1KMT2AMAPTLMNA
SCHEMBL8350541 1.00 TDP1 (0.48) TDP1MEN1KMT2AMAPTLMNA
Water SCHEMBL10717096 0.98 TDP1 (0.47) TDP1MEN1KMT2AMAPTLMNA
SCHEMBL37039 0.94 TDP1 (0.53) TDP1MAPTLMNACYP2D6TSHR
SCHEMBL30950765 0.94 TDP1 (0.53) TDP1MAPTLMNACYP2D6TSHR
Terephthalic Acid SCHEMBL28124476 0.94 TDP1 (0.53) TDP1MAPTLMNACYP2D6TSHR
SCHEMBL12446490 0.92 TDP1 (0.52) TDP1MAPTLMNACYP2D6TSHR
Bicarbonate SCHEMBL6905502 0.92 TDP1 (0.52) TDP1MAPTLMNACYP2D6TSHR
Water SCHEMBL2784554 0.92 TDP1 (0.52) TDP1MAPTLMNACYP2D6TSHR
SCHEMBL10329337 0.92 TDP1 (0.52) TDP1MAPTLMNACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110331467-B Superfine denier spandex interwoven with terylene and preparation method thereof 郑州中远氨纶工程技术有限公司 2021-10-26 CN disclosed
CN-104039197-A Cosmetic Applicator KAO CORP 2014-09-10 CN disclosed
CN-101029121-A Mixed thermoplastic polyester and heat shrinkable sleeve made of same NANYA PLASTIC IND CO LTD (CN) 2007-09-05 CN disclosed
US-5912275-A BY METHSNOLYSIS AND RECOVERY OF METHANOL USING AZORTROPICAGENTS METHYL BENZOATE OR PARA METHYL TOLUATE. E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-06-15 US disclosed