SCHEMBL8344899

SCHEMBL8344899

CCOC(C)OCC.O=CCOc1cc(Cl)c(OCCCOc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 4/20 0.35
DRD2 P14416 3/20 0.35
DRD3 P35462 3/20 0.35
KCNA3 P22001 2/20 0.34
ALDH1A1 P00352 3/20 0.34
ORAI1 Q96D31 1/20 0.34
MAPT P10636 3/20 0.33
FFAR1 O14842 2/20 0.33
LMNA P02545 2/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ABCB11 O95342 1/20 0.33
MAPK1 P28482 1/20 0.33
PPARA Q07869 1/20 0.33
APOBEC3A P31941 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HRH2 P25021 1/20 0.32
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8341250 0.88 DRD4 (0.41) DRD4DRD2DRD3KCNA3ALDH1A1
SCHEMBL8339293 0.86 PPARA (0.36) FFAR1PPARA
SCHEMBL10944086 0.85 FFAR1 (0.41) DRD4DRD2DRD3ALDH1A1MAPT
SCHEMBL5645717 0.79 FFAR1 (0.43) ALDH1A1FFAR1LMNASMN1; SMN2MEN1
SCHEMBL8344905 0.78 DRD4 (0.37) DRD4DRD2DRD3KCNA3MAPT
SCHEMBL5648390 0.73 PPARG (0.44) ALDH1A1MAPTFFAR1LMNASMN1; SMN2
SCHEMBL8408726 0.73 HTT (0.42) DRD4DRD2DRD3KCNA3ALDH1A1
SCHEMBL8341924 0.72 PPARA (0.39) ALDH1A1PPARACTDSP1
SCHEMBL11514845 0.72 PPARG (0.43) DRD4DRD2DRD3LMNAPPARA
SCHEMBL8346276 0.72 DRD4 (0.38) DRD4DRD2DRD3KCNA3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed