Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780392 | 0.89 | PTPN7 (0.70) | GAALMNANPC1TDP1PTPN7 | |
| SCHEMBL11008109 | 0.88 | GAA (0.70) | GAALMNANPC1L3MBTL1TDP1 | |
| SCHEMBL10784413 | 0.88 | TDP1 (0.60) | GAALMNANPC1L3MBTL1TDP1 | |
| SCHEMBL10199128 | 0.84 | GAA (0.76) | GAALMNANPC1L3MBTL1TDP1 | |
| SCHEMBL10597791 | 0.84 | GAA (0.76) | GAALMNANPC1L3MBTL1TDP1 | |
| SCHEMBL7653097 | 0.83 | PTPN7 (0.65) | GAANPC1L3MBTL1TDP1PTPN7 | |
| SCHEMBL9787019 | 0.82 | PTPN7 (0.59) | LMNANPC1L3MBTL1TDP1PTPN7 | |
| Toluene SCHEMBL5468703 | 0.81 | PTPN7 (0.84) | LMNANPC1TDP1PTPN7POLB | |
| SCHEMBL27370553 | 0.81 | PTPN7 (0.63) | GAAPTPN7POLBRAB9AMEN1 | |
| SCHEMBL30360394 | 0.81 | PTPN7 (0.67) | LMNANPC1PTPN7POLBRAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36321-E | INCLUDING DIARYL DIETHER COMPOUND | KANSAKI PAPER MANUFACTURING CO., LTD. (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0141170-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-05-13 | — | — | EP | disclosed |
| US-4531140-A | Heat-sensitive recording material | Kansaki Paper Manufacturing Co. Ltd. (JP) | 1985-07-23 | — | — | US | disclosed |
| EP-0141170-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1985-05-15 | — | — | EP | disclosed |