Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713910 | 0.90 | MAPT (0.61) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6714247 | 0.87 | MAPT (0.62) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8346734 | 0.87 | MAPT (0.62) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6716813 | 0.87 | MAPT (0.62) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6714044 | 0.83 | MAPT (0.61) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6715869 | 0.82 | MAPT (0.59) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6717225 | 0.81 | MAPT (0.58) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6717221 | 0.80 | MAPT (0.62) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6713855 | 0.79 | MAPT (0.56) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6723389 | 0.79 | MAPT (0.56) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022534-A1 | ARYLGLYCINE DERIVATIVES FOR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |