Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.58 |
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593327 | 0.92 | F10 (0.69) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL4593658 | 0.83 | F10 (0.69) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL4593751 | 0.83 | F10 (0.69) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL4593322 | 0.79 | F10 (0.62) | F10F2SLC29A1 | |
| SCHEMBL4593964 | 0.78 | F10 (0.64) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4594060 | 0.78 | F10 (0.63) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL2003292 | 0.77 | F10 (0.70) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL4586496 | 0.74 | F10 (0.70) | F10F2PDE4APDE4BPDE4C | |
| SCHEMBL4594024 | 0.74 | F10 (0.64) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL5641092 | 0.73 | F10 (1.00) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004083174-A2 | SULFONYL-AMIDINO CONTAINING AND TETRAHYDROPYRIMIDINO CONTAINING COMPOUNDS AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |