Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.75 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794795 | 0.89 | CDC7 (0.79) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL16456794 | 0.87 | CDC7 (0.77) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL2822677 | 0.86 | CDC7 (0.75) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL5735273 | 0.86 | CDC7 (1.00) | CDC7DBF4ALDH1A1HPGD | |
| SCHEMBL2225549 | 0.86 | CDC7 (0.79) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL28245818 | 0.85 | CDC7 (0.73) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL4894167 | 0.85 | CDC7 (0.73) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL18974750 | 0.84 | NPC1 (0.68) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL23146398 | 0.84 | CDC7 (0.71) | CDC7DBF4SMN1; SMN2MAPTTRPM8 | |
| SCHEMBL20894373 | 0.83 | CDC7 (0.71) | CDC7DBF4MAPTTRPM8HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888941-A | Carbozamides with antifungal activity | J. URIACH & CIA. S.A. (ES) | 1999-03-30 | — | — | US | disclosed |
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997005131-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-02-13 | — | — | WO | disclosed |