⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1112946 | 1.00 | — | — | |
| SCHEMBL1112944 | 1.00 | — | — | |
| SCHEMBL1540574 | 1.00 | — | — | |
| SCHEMBL1540185 | 1.00 | — | — | |
| SCHEMBL1540577 | 1.00 | — | — | |
| SCHEMBL20738 | 1.00 | — | — | |
| SCHEMBL1540182 | 1.00 | — | — | |
| SCHEMBL1540183 | 1.00 | — | — | |
| SCHEMBL1540579 | 1.00 | — | — | |
| SCHEMBL23927998 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220040318-A1 | PRIMARY AMINE COMPOUND OR SECONDARY AMINE COMPOUND-ACIDIC POLYSACCHARIDE CONJUGATE AND PRODUCTION METHOD THEREFOR | SEIKAGAKU CORPORATION (JP) | 2022-02-10 | — | — | US | disclosed |
| US-20220023275-A1 | Aqueous Based Pharmaceutical Formulations of 1,2-Dihydropyridine Compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| EP-3893844-A1 | AQUEOUS BASED PHARMACEUTICAL FORMULATIONS OF 1,2-DIHYDROPYRIDINE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2021-10-20 | — | — | EP | disclosed |
| CN-113226286-A | Water-based pharmaceutical formulations of 1, 2-dihydropyridine compounds | 卫材R&D管理有限公司 | 2021-08-06 | — | — | CN | disclosed |
| US-20210147405-A1 | BICYCLIC HETEROAROMATIC UREA OR CARBAMATE COMPOUNDS FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2021-05-20 | — | — | US | disclosed |
| US-20210015933-A1 | BIOACTIVE CARBOXYLIC ACID TYPE COMPOUND-POLYMER CONJUGATE, AND METHOD FOR MANUFACTURING THE SAME | SEIKAGAKU CORPORATION (JP) | 2021-01-21 | — | — | US | disclosed |
| US-20200223837-A1 | BENZOFURAN AMIDES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2020-07-16 | — | — | US | disclosed |
| US-20200216435-A1 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2020-07-09 | — | — | US | disclosed |
| WO-2020124090-A1 | AQUEOUS BASED PHARMACEUTICAL FORMULATIONS OF 1,2-DIHYDROPYRIDINE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-06-18 | — | — | WO | disclosed |
| US-20200138964-A1 | TERTIARY AMINE COMPOUND OR IMINE COMPOUND-POLYMER CONJUGATE AND PRODUCTION METHOD THEREFOR | SEIKAGAKU CORPORATION (JP) | 2020-05-07 | — | — | US | disclosed |
| US-4294757-A | BLEACHING CELLULOSE FIBERS AND ADDITION OF ALKALI METAL POLYPHOSPHATES AND ALKALI METAL DIETHYLENETRIAMINE PENTA(METHYLENE PHOSPHONAT) | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1981-10-13 | — | — | US | disclosed |
| US-4263294-A | ANTITUMOUR AGENTS, ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4260608-A | ANTIMICROBIAL, ANTIMITOTIC, AND ANTITUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-04-07 | — | — | US | disclosed |
| US-4256746-A | ANTITUMOR AGENTS; MICROBIOCIDES; MITOSIS | TAKEDA CHEMICAL INDUSTRIES (JP) | 1981-03-17 | — | — | US | disclosed |
| US-4248870-A | MICROBIOCIDES, ANTITUMOR AGENTS, AND ANTIMITOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-02-03 | — | — | US | disclosed |
| EP-0014402-A1 | Novel 20-0-acylmaytansinoids, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-08-20 | — | — | EP | disclosed |
| EP-0011302-A1 | Maytansinoids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1980-05-28 | — | — | EP | disclosed |
| EP-0011276-A1 | Maytansinoids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1980-05-28 | — | — | EP | disclosed |
| EP-0011277-A1 | Dechloromaytansinoids, their production and use and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-05-28 | — | — | EP | disclosed |
| EP-0010735-A1 | Maytansinoids, their production and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1980-05-14 | — | — | EP | disclosed |