SCHEMBL8345285

SCHEMBL8345285

Cc1cc(OC/C=C(/F)Cl)cc(Cl)c1OCCCOc1ccc(C(F)(F)F)cn1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
MAPK1 P28482 1/20 0.35
LIPE Q05469 5/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
PPARG P37231 2/20 0.33
PPARD Q03181 2/20 0.33
PPARA Q07869 2/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 2/20 0.32
SCN9A Q15858 1/20 0.32
GABRA5 P31644 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8345287 1.00 KMT2A (0.35) KMT2AMAPK1LIPEL3MBTL1MRGPRX4
SCHEMBL7075429 0.93 KMT2A (0.36) KMT2AMAPK1LIPEL3MBTL1MRGPRX4
SCHEMBL8409017 0.93 KMT2A (0.39) KMT2AMAPK1LIPEL3MBTL1MRGPRX4
SCHEMBL8409018 0.93 KMT2A (0.39) KMT2AMAPK1LIPEL3MBTL1MRGPRX4
SCHEMBL8338445 0.91 KMT2A (0.35) KMT2AMAPK1LIPEL3MBTL1MRGPRX4
SCHEMBL8338444 0.91 KMT2A (0.35) KMT2AMAPK1LIPEL3MBTL1MRGPRX4
SCHEMBL7073130 0.91 KMT2A (0.36) KMT2AMAPK1LIPEL3MBTL1MRGPRX4
SCHEMBL8341315 0.87 PPARD (0.38) PPARGPPARDPPARA
SCHEMBL8341308 0.87 PPARD (0.38) PPARGPPARDPPARA
Pyridalyl SCHEMBL83386 0.86 KMT2A (0.39) KMT2AMAPK1LIPEL3MBTL1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed