SCHEMBL834529

SCHEMBL834529

CN(C(=O)NCCc1ccccc1)[C@@H]1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL833442 1.00 PTGDR2 (0.68) PTGDR2
SCHEMBL833443 1.00 PTGDR2 (0.68) PTGDR2
SCHEMBL834648 0.91 PTGDR2 (0.70) PTGDR2
SCHEMBL834647 0.91 PTGDR2 (0.70) PTGDR2
SCHEMBL833487 0.88 PTGDR2 (0.70) PTGDR2
SCHEMBL833486 0.88 PTGDR2 (0.70) PTGDR2
SCHEMBL1905370 0.84 PTGDR2 (0.48) PTGDR2
SCHEMBL1905371 0.84 PTGDR2 (0.48) PTGDR2
SCHEMBL831405 0.84 PTGDR2 (0.65) PTGDR2
SCHEMBL831404 0.84 PTGDR2 (0.65) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143304-B2 (3-amino-1,2,3,4-tetrahydro-9 H-carbazol-9-yl)-acetic acid derivatives ACTELION PHARMACEUTICAL LTD. (CH) 2012-03-27 US claimed