SCHEMBL8345337

SCHEMBL8345337

CC(C)Oc1ccc(OCCCOc2c(Cl)cc(OCC=C(F)Cl)cc2Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.38
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
KMT2A Q03164 1/20 0.35
PPARD Q03181 3/20 0.35
PPARA Q07869 3/20 0.35
FFAR4 Q5NUL3 1/20 0.33
HTT P42858 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
RECQL P46063 1/20 0.32
NSD2 O96028 1/20 0.32
HPGD P15428 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
RAB9A P51151 1/20 0.31
PTGDR Q13258 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8345335 1.00 PLAU (0.38) PLAUALDH1A1KDM4EKMT2APPARD
SCHEMBL8341260 0.91 TP53 (0.34) PLAUALDH1A1KDM4EKMT2APPARD
SCHEMBL8341261 0.91 TP53 (0.34) PLAUALDH1A1KDM4EKMT2APPARD
SCHEMBL8406348 0.91 HTT (0.40) PLAUALDH1A1KDM4EKMT2APPARD
SCHEMBL8345846 0.90 PLAU (0.37) PLAUALDH1A1KDM4EKMT2APPARD
SCHEMBL8345844 0.90 PLAU (0.37) PLAUALDH1A1KDM4EKMT2APPARD
SCHEMBL8407599 0.88 HTT (0.40) PLAUALDH1A1KDM4EKMT2APPARD
SCHEMBL8341162 0.87 DRD4 (0.37) ALDH1A1KMT2APPARAHTTHPGD
SCHEMBL8341168 0.87 DRD4 (0.37) ALDH1A1KMT2APPARAHTTHPGD
SCHEMBL8345716 0.84 DRD4 (0.38) KDM4EKMT2APPARDHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed