SCHEMBL8345352

SCHEMBL8345352

F/C(Br)=C/COc1cc(Cl)c(OCCCOc2ccc(Br)cc2)c(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 3/20 0.41
PPARD Q03181 3/20 0.36
DRD2 P14416 2/20 0.35
DRD3 P35462 2/20 0.35
L3MBTL1 Q9Y468 3/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TAOK1 Q7L7X3 1/20 0.32
TAOK3 Q9H2K8 1/20 0.32
MAOB P27338 2/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8345354 1.00 DRD4 (0.41) DRD4PPARDDRD2DRD3L3MBTL1
SCHEMBL8345741 0.91 DRD4 (0.39) DRD4DRD2DRD3L3MBTL1MAPT
SCHEMBL8345739 0.91 DRD4 (0.39) DRD4DRD2DRD3L3MBTL1MAPT
SCHEMBL8345716 0.90 DRD4 (0.38) DRD4PPARDDRD2DRD3L3MBTL1
SCHEMBL8345714 0.90 DRD4 (0.38) DRD4PPARDDRD2DRD3L3MBTL1
SCHEMBL8411908 0.89 DRD4 (0.39) DRD4DRD2DRD3ALDH1A1
SCHEMBL8411906 0.89 DRD4 (0.39) DRD4DRD2DRD3ALDH1A1
SCHEMBL8405387 0.87 HTT (0.40) DRD4PPARDDRD2DRD3L3MBTL1
SCHEMBL8345042 0.87 FFAR4 (0.40) PPARDMAOBATM
SCHEMBL8345045 0.87 FFAR4 (0.40) PPARDMAOBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0787710-B1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1999-07-28 EP disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed