Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559757 | 0.79 | TDP1 (0.36) | TYMS | |
| SCHEMBL8108530 | 0.76 | — | — | |
| SCHEMBL5852653 | 0.76 | TDP1 (0.32) | — | |
| SCHEMBL6967039 | 0.73 | KCNA5 (0.32) | — | |
| SCHEMBL8349719 | 0.73 | KCNA5 (0.37) | — | |
| SCHEMBL8500182 | 0.71 | — | — | |
| SCHEMBL8346651 | 0.70 | HSP90B1 (0.32) | TYMS | |
| SCHEMBL8102069 | 0.69 | — | — | |
| SCHEMBL8100145 | 0.67 | CCNE2 (0.34) | — | |
| SCHEMBL6973234 | 0.65 | GSK3B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |