Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 16/20 | 0.55 |
| ▸ | F2 | P00734 | 15/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345139 | 1.00 | PRSS1 (0.55) | PRSS1F2EPHX1 | |
| SCHEMBL8340036 | 1.00 | PRSS1 (0.55) | PRSS1F2EPHX1 | |
| SCHEMBL8339855 | 1.00 | PRSS1 (0.55) | PRSS1F2EPHX1 | |
| SCHEMBL8342304 | 1.00 | PRSS1 (0.55) | PRSS1F2EPHX1 | |
| SCHEMBL8345820 | 0.99 | PRSS1 (0.54) | PRSS1F2 | |
| SCHEMBL8339478 | 0.94 | PRSS1 (0.49) | PRSS1F2 | |
| SCHEMBL8345424 | 0.93 | PRSS1 (0.49) | PRSS1F2 | |
| SCHEMBL8341867 | 0.93 | PRSS1 (0.49) | PRSS1F2 | |
| SCHEMBL8340107 | 0.91 | PRSS1 (0.45) | PRSS1F2 | |
| SCHEMBL8341977 | 0.90 | PRSS1 (0.57) | PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917034-A | Antithrombotic n-amidinopiperidine and benzamidine derivatives | PFIZER INC. (US) | 1999-06-29 | — | — | US | disclosed |