Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064299 | 0.88 | HDAC1 (0.77) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL8346278 | 0.86 | HDAC1 (0.58) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL12933622 | 0.82 | HDAC1 (0.73) | HDAC1HDAC2HDAC3NCOR2KCNQ3 | |
| SCHEMBL1063281 | 0.81 | HDAC1 (0.72) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL211732 | 0.79 | HDAC1 (0.84) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL8291906 | 0.77 | HDAC1 (0.60) | HDAC1HDAC2 | |
| SCHEMBL1066534 | 0.77 | HDAC1 (0.74) | HDAC1HDAC2 | |
| SCHEMBL1064557 | 0.76 | HDAC1 (1.00) | HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL8293250 | 0.76 | HDAC1 (0.49) | HDAC1HDAC2 | |
| SCHEMBL1068398 | 0.76 | HDAC1 (0.76) | HDAC1HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069823-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2004-08-19 | — | — | WO | disclosed |