Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 3/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123288 | 0.94 | EPHX1 (0.41) | EPHX1TDP1DRD2MAOAMAOB | |
| SCHEMBL8117400 | 0.93 | TDP1 (0.42) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL5963740 | 0.93 | TDP1 (0.42) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL24517024 | 0.80 | EPHX1 (0.41) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL25961857 | 0.80 | EPHX1 (0.41) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL30605383 | 0.77 | EPHX1 (0.43) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL26966258 | 0.77 | EPHX1 (0.43) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL30605405 | 0.77 | EPHX1 (0.43) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL26966421 | 0.77 | EPHX1 (0.43) | EPHX1TDP1DRD2ACACBKMT2A | |
| SCHEMBL24517021 | 0.77 | EPHX1 (0.43) | EPHX1TDP1DRD2ACACBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999022735-A1 | SOMATOSTATIN AGONISTS | MERCK & CO., INC. (US) | 1999-05-14 | — | — | WO | disclosed |