Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547779 | 0.86 | ELANE (0.51) | ELANECYP2C9 | |
| SCHEMBL13089737 | 0.80 | ELANE (0.44) | ALDH1A1ELANECYP2C9MEN1KMT2A | |
| SCHEMBL8346759 | 0.77 | ELANE (0.54) | ELANECYP2C9 | |
| SCHEMBL4547783 | 0.76 | ELANE (0.48) | ELANECYP2C9 | |
| SCHEMBL4547772 | 0.75 | ELANE (0.46) | ELANECYP2C9 | |
| SCHEMBL2678883 | 0.74 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL4547770 | 0.74 | ELANE (0.45) | ELANECYP2C9 | |
| SCHEMBL4547771 | 0.72 | ELANE (0.46) | ALDH1A1KDM4EHTTELANECYP2C9 | |
| SCHEMBL4547768 | 0.72 | ELANE (0.47) | ELANECYP2C9 | |
| SCHEMBL4547785 | 0.71 | ELANE (0.49) | ELANECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024701-A1 | HETEROCYCLIC DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-03-25 | — | — | WO | disclosed |