Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 11/20 | 0.56 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755279 | 0.86 | SRD5A1 (0.75) | SRD5A2SRD5A1AR | |
| SCHEMBL8892299 | 0.86 | SRD5A1 (0.75) | SRD5A2SRD5A1AR | |
| SCHEMBL9022319 | 0.86 | SRD5A2 (0.75) | SRD5A2SRD5A1AR | |
| SCHEMBL9022310 | 0.86 | SRD5A2 (0.75) | SRD5A2SRD5A1AR | |
| SCHEMBL8353236 | 0.83 | SRD5A1 (0.56) | SRD5A2SRD5A1 | |
| SCHEMBL9021941 | 0.82 | SRD5A2 (0.69) | SRD5A2SRD5A1AR | |
| SCHEMBL9021951 | 0.82 | SRD5A2 (0.69) | SRD5A2SRD5A1AR | |
| SCHEMBL9022187 | 0.82 | SRD5A2 (0.68) | SRD5A2SRD5A1AR | |
| SCHEMBL9022179 | 0.82 | SRD5A2 (0.68) | SRD5A2SRD5A1AR | |
| SCHEMBL8016669 | 0.81 | SRD5A2 (0.58) | SRD5A2SRD5A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748221-B1 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1999-04-14 | — | — | EP | claimed |
| US-5872126-A | ENZYME INHIBITORS FOR TREATMENT OF PREMATURE LABOR | MERCK & CO., INC. (US) | 1999-02-16 | — | — | US | claimed |
| WO-1998009632-A1 | METHODS AND COMPOSITIONS FOR TREATING PRETERM LABOR | MERCK & CO., INC. (US) | 1998-03-12 | — | — | WO | claimed |
| EP-0748221-A1 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0748221-A4 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1996-10-07 | — | — | EP | claimed |
| WO-1995012398-A1 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1995-05-11 | — | — | WO | claimed |
| EP-0748221-B1 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5872126-A | ENZYME INHIBITORS FOR TREATMENT OF PREMATURE LABOR | MERCK & CO., INC. (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0748221-A1 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0748221-A4 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1996-10-07 | — | — | EP | disclosed |
| WO-1995012398-A1 | 7-SUBSTITUTED-4-AZA-STEROID DERIVATIVES AS 5-ALPHA- REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1995-05-11 | — | — | WO | disclosed |