Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.68 |
| ▸ | F3 | P13726 | 20/20 | 0.68 |
| ▸ | F10 | P00742 | 12/20 | 0.52 |
| ▸ | F2 | P00734 | 11/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | F11 | P03951 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349064 | 0.91 | F7 (0.83) | F7F3F10F2PRSS1 | |
| SCHEMBL6786955 | 0.90 | F7 (0.83) | F7F3F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL6027226 | 0.85 | F7 (0.77) | F7F3F10F2PRSS1 | |
| SCHEMBL6788956 | 0.81 | F7 (1.00) | F7F3F10F2PRSS1 | |
| SCHEMBL6026692 | 0.78 | F7 (0.83) | F7F3F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL5048828 | 0.78 | F7 (0.92) | F7F3F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL6027413 | 0.77 | F7 (0.81) | F7F3F10F2PRSS1 | |
| SCHEMBL8302861 | 0.75 | F7 (0.69) | F7F3F10F2PRSS1 | |
| SCHEMBL8300552 | 0.74 | F7 (0.49) | F7F3F10F2PRSS1 | |
| SCHEMBL8348371 | 0.70 | CYP1A2 (0.44) | F7F3F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072101-A2 | PHENYLGLYCINE DERIVATIVES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-08-26 | — | — | WO | disclosed |