Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837682 | 0.82 | CA1 (0.40) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL28375583 | 0.78 | CA1 (0.42) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL12628457 | 0.78 | CA1 (0.45) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL21010838 | 0.78 | CA1 (0.45) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL13355820 | 0.78 | CA1 (0.50) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL5406627 | 0.73 | AKR1C4 (0.38) | CA1CA9CYP1A2 | |
| SCHEMBL5905609 | 0.72 | CYP1A2 (0.45) | CA1CYP1A2PRKCAPPARG | |
| SCHEMBL28371484 | 0.71 | CA1 (0.41) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL13105428 | 0.71 | SMN1; SMN2 (0.41) | PRKCAPPARG | |
| SCHEMBL29766187 | 0.71 | SMN1; SMN2 (0.41) | PRKCAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101659-A1 | METHODS FOR INCREASING MOLECULAR DIVERSITY OF POLYKETIDES AND NON-RIBOSOMAL PROTEINS | Isomerase Therapeutics Ltd. (GB) | 2017-04-13 | — | — | US | disclosed |
| EP-1967520-A2 | Production of polyketides and other natural products | Biotica Technology Limited (GB) | 2008-09-10 | — | — | EP | disclosed |
| WO-2004007709-A2 | PRODUCTION OF POLYKETIDES | BIOTICA TECHNOLOGY LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |