Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.59 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060306 | 0.88 | DAO (0.60) | DAOB3GNT2MEN1KMT2AALDH1A1 | |
| SCHEMBL6058994 | 0.82 | DAO (0.57) | DAOB3GNT2MEN1KMT2ACYP1A2 | |
| SCHEMBL6060512 | 0.82 | DAO (0.57) | DAOB3GNT2MEN1KMT2ACYP1A2 | |
| SCHEMBL14326956 | 0.82 | KMT2A (0.62) | DAOMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL13801870 | 0.81 | B3GNT2 (0.51) | DAOB3GNT2MEN1KMT2AALDH1A1 | |
| SCHEMBL6060274 | 0.79 | IDO1 (0.58) | DAOB3GNT2MEN1KMT2AALDH1A1 | |
| SCHEMBL10169863 | 0.79 | KMT2A (0.55) | DAOMEN1KMT2AALDH1A1GRIN1 | |
| SCHEMBL2267066 | 0.79 | CYP1A2 (0.67) | DAOB3GNT2MEN1KMT2AALDH1A1 | |
| SCHEMBL11705078 | 0.78 | DAO (0.55) | DAOMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6059727 | 0.78 | DAO (0.59) | DAOMEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052847-A2 | TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |