SCHEMBL8349339

SCHEMBL8349339

N[C@H]1CCC(=O)OC(=O)C[C@H](N)C(=O)OC1=O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.34
GMNN O75496 1/20 0.34
PPM1B O75688 1/20 0.34
LMNA P02545 1/20 0.34
PPP1CC P36873 1/20 0.34
TFPI2 P48307 1/20 0.34
RAB9A P51151 1/20 0.34
PPP5C P53041 1/20 0.34
PPP1CA P62136 1/20 0.34
PMP22 Q01453 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TP53 P04637 1/20 0.34
CYP2D6 P10635 1/20 0.34
NFKB1 P19838 1/20 0.34
THPO P40225 1/20 0.34
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2638214 0.92 TSHR (0.46) TSHRKDM4EGMNNPPM1BLMNA
SCHEMBL14125402 0.85 TSHR (0.50) TSHRKDM4EGMNNPPM1BLMNA
SCHEMBL9718442 0.85 TSHR (0.50) TSHR
SCHEMBL5495656 0.85
SCHEMBL496859 0.85
Hydrochloric Acid SCHEMBL10636423 0.83 TSHR (0.39) TSHRKDM4EGMNNPPM1BLMNA
SCHEMBL238394 0.80
SCHEMBL1484120 0.80
SCHEMBL8060861 0.80
SCHEMBL5165814 0.78 TSHR (0.37) TSHRCA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999032887-A1 DETECTION OF PROSTATE DISEASE BY MEASURING NAALADASE ACTIVITY GUILFORD PHARMACEUTICALS INC. (US) 1999-07-01 WO claimed
EP-4676472-A2 BI-SPECIFIC ADAPTERS AND THEIR USE WITH UNIVERSAL CAR-T CELLS IN THE TREATMENT OF TUMORS AND THE INHIBITION OF CANCER-ASSOCIATED FIBROBLASTS Purdue Research Foundation (US) 2026-01-14 EP disclosed
CN-119367415-A Application of MLCT in preparation of medicine for preventing and/or treating non-alcoholic fatty liver disease 浙江科技大学 2025-01-28 CN disclosed
WO-2024191886-A9 BI-SPECIFIC ADAPTERS AND THEIR USE WITH UNIVERSAL CAR-T CELLS IN THE TREATMENT OF TUMORS AND THE INHIBITION OF CANCER-ASSOCIATED FIBROBLASTS PURDUE RESEARCH FOUNDATION (US) 2024-12-05 WO disclosed
US-20240307423-A1 FRACTIONS OF, AND MOLECULES RELEASED IN, PROTEIN RICH PLASMA WHICH INHIBIT IMMUNE RESPONSES AND REDUCE INFLAMMATION, AND METHODS OF OBTAINING New York Society for the Relief of the Ruptured and Crippled, Maintaining the Hospital for Special S (US) 2024-09-19 US disclosed
WO-2024191886-A2 BI-SPECIFIC ADAPTERS AND THEIR USE WITH UNIVERSAL CAR-T CELLS IN THE TREATMENT OF TUMORS AND THE INHIBITION OF CANCER-ASSOCIATED FIBROBLASTS PURDUE RESEARCH FOUNDATION (US) 2024-09-19 WO disclosed
WO-2022173935-A1 FRACTIONS OF, AND MOLECULES RELEASED IN, PROTEIN RICH PLASMA WHICH INHIBIT IMMUNE RESPONSES AND REDUCE INFLAMMATION, METHODS OF USE AND METHODS OF OBTAINING NEW YORK SOCIETY FOR THE RELIEF OF THE RUPTURED AND CRIPPLED, MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY (US) 2022-08-18 WO disclosed
CN-105636924-A Labeled inhibitors of Prostate Specific Membrane Antigen (PSMA), their use as imaging agents and agents for treating prostate cancer DEUTSCHES KREBSFORSCH 2016-06-01 CN disclosed
WO-1999032887-A1 DETECTION OF PROSTATE DISEASE BY MEASURING NAALADASE ACTIVITY GUILFORD PHARMACEUTICALS INC. (US) 1999-07-01 WO disclosed
EP-0660707-A4 METHOD OF PREVENTING NMDA RECEPTOR-MEDIATED NEURONAL DAMAGE. CHILDRENS MEDICAL CENTER (US) 1998-05-13 EP disclosed
EP-0660707-A1 METHOD OF PREVENTING NMDA RECEPTOR-MEDIATED NEURONAL DAMAGE The Children's Medical Center Corporation (US) 1995-07-05 EP disclosed
WO-1994005275-A1 METHOD OF PREVENTING NMDA RECEPTOR-MEDIATED NEURONAL DAMAGE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1994-03-17 WO disclosed