Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409341 | 0.87 | PTGDR2 (0.72) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7408565 | 0.85 | PTGDR2 (0.71) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| SCHEMBL2311331 | 0.80 | PTGDR2 (0.60) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| SCHEMBL832500 | 0.79 | PTGDR2 (0.65) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| SCHEMBL16561901 | 0.79 | PTGDR2 (0.65) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| SCHEMBL2310848 | 0.79 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL3020302 | 0.78 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL3020304 | 0.78 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| SCHEMBL4509853 | 0.78 | PTGDR2 (0.77) | PTGDR2TBXA2RPTGDRKDM4EMEN1 | |
| SCHEMBL2309815 | 0.77 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143304-B2 | (3-amino-1,2,3,4-tetrahydro-9 H-carbazol-9-yl)-acetic acid derivatives | ACTELION PHARMACEUTICAL LTD. (CH) | 2012-03-27 | — | — | US | claimed |