Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.70 |
| ▸ | TACR3 | P29371 | 2/20 | 0.66 |
| ▸ | TACR2 | P21452 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | FPR1 | P21462 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428892 | 1.00 | TACR1 (0.70) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL7026820 | 1.00 | TACR1 (0.70) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL8353379 | 0.96 | TACR1 (0.66) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL8353376 | 0.96 | TACR1 (0.66) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL7022339 | 0.94 | TACR1 (0.76) | TACR1TACR3TACR2 | |
| SCHEMBL264224 | 0.94 | TACR1 (0.76) | TACR1TACR3TACR2 | |
| SCHEMBL264225 | 0.94 | TACR1 (0.76) | TACR1TACR3TACR2 | |
| SCHEMBL265029 | 0.90 | TACR1 (0.59) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL265028 | 0.90 | TACR1 (0.59) | TACR1TACR3TACR2NR3C1CYP3A4 | |
| SCHEMBL8151210 | 0.86 | TACR1 (0.53) | TACR1TACR3TACR2NR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891875-A | Morpholinyl tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1999-04-06 | — | — | US | disclosed |