SCHEMBL835069

SCHEMBL835069

Cc1cc(C(=O)O)sc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 6/20 1.00
KDM4E B2RXH2 3/20 1.00
MAPT P10636 3/20 1.00
MEN1 O00255 2/20 1.00
ALDH1A1 P00352 2/20 1.00
KMT2A Q03164 2/20 1.00
ALOX15 P16050 2/20 0.53
GPR35 Q9HC97 4/20 0.46
HCAR2 Q8TDS4 1/20 0.43
GLA P06280 1/20 0.42
PKM P14618 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TP53 P04637 1/20 0.42
GAA P10253 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14391009 0.82 DAO (0.69) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL5850753 0.81 MAPT (0.68) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL9925990 0.80 KDM4E (0.67) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL3093344 0.79 DAO (0.65) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL2333545 0.79 MAPT (0.65) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL1529585 0.77 DAO (1.00) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL1472954 0.77 DAO (0.63) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL4062257 0.77 DAO (0.63) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL7816128 0.77 DAO (0.63) DAOKDM4EMAPTMEN1ALDH1A1
SCHEMBL1529532 0.77 DAO (0.63) DAOKDM4EMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12408914-B2 Systems and methods for customizing mechanical strength in stimuli-responsive bioabsorbable materials CILAG GMBH INTERNATIONAL (CH) 2025-09-09 US disclosed
EP-4543502-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS Cilag GmbH International (CH) 2025-04-30 EP disclosed
WO-2024261659-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 WO disclosed
US-20240423620-A1 COMPRESSIBLE SURGICAL ADJUNCTS, CARTRIDGES, AND CARTRIDGE ASSEMBLIES AND METHODS OF MAKING SURGICAL ADJUNCTS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
US-20240423617-A1 SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
US-20240382613-A1 METHODS AND SYSTEMS FOR ULTRASOUND STIMULATED STRUCTURES AND DELIVERY OF THERAPEUTIC SPECIES THE PENN STATE RESEARCH FOUNDATION 2024-11-21 US disclosed
EP-4447944-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES THE PENN STATE RESEARCH FOUNDATION (US) 2024-10-23 EP disclosed
US-20240335540-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES PENN STATE RES FOUND (US) 2024-10-10 US disclosed
CN-118613287-A Compositions and methods for targeted delivery of therapeutic and/or diagnostic substances 宾夕法尼亚州立大学研究基金会 2024-09-06 CN disclosed
EP-4398985-A2 METHODS AND SYSTEMS FOR ULTRASOUND STIMULATED STRUCTURES AND DELIVERY OF THERAPEUTIC SPECIES The Penn State Research Foundation (US) 2024-07-17 EP disclosed
CN-1280300-C Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers BASELL TECHNOLOGY CO BV (NL) 2006-10-18 CN disclosed
US-7112638-B2 Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers BASELL POLYOLEFINE GMBH (DE) 2006-09-26 US disclosed
US-20030036612-A1 Hetero cyclic metallocene compounds and use thereof in catalyst system for producing olefin polymers BASELL POLYOLEFINE GMBH (DE) 2003-02-20 US disclosed
CN-1348459-A Heterocyclic metallocene compounds and their use in catalyst systems for producing olefin polymers BASELL TECHNOLOGY CO BV (NL) 2002-05-08 CN disclosed
EP-1157027-A1 HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS Basell Technology Company B.V. (NL) 2001-11-28 EP disclosed
WO-2001047939-A1 HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-07-05 WO disclosed
WO-1998042347-A1 PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-01 WO disclosed
EP-0382106-B1 Process for manufacturing thiophene derivatives HOECHST AG (DE) 1995-06-07 EP disclosed
US-5100520-A Electrochemical Dehalogenation HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed
EP-0382106-A2 Process for manufacturing thiophene derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240382613-A1 METHODS AND SYSTEMS FOR ULTRASOUND STIMULATED STRUCTURES AND DELIVERY OF THERAPEUTIC SPECIES PAICS, APEX1, ADM2 DAO 676/4885KDM4E 3785/4885MAPT 1264/4885
US-20240335540-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES PAICS, CD47, CA13 DAO 893/4885KDM4E 3564/4885MAPT 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.