Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.70 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.66 |
| ▸ | FGF2 | P09038 | 1/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | OSBP | P22059 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.62 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.62 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.57 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 2/20 | 0.54 |
| ▸ | UGCG | Q16739 | 2/20 | 0.54 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8398569 | 1.00 | POLA1 (0.70) | POLA1CYP46A1FGF2USP2OSBP | |
| Trifluoroacetic Acid SCHEMBL8398572 | 1.00 | POLA1 (0.70) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL30862600 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL17149739 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL4370706 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL12500755 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL30862603 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL30862601 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL27417377 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP | |
| SCHEMBL27321810 | 0.94 | POLA1 (0.75) | POLA1CYP46A1FGF2USP2OSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885968-A | FOR HYPOLIPIDEMIC MEDICINES | RIJKSUNIVERSITEIT TE LEIDEN (NL) | 1999-03-23 | — | — | US | disclosed |
| EP-0655070-B1 | TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE | UNIV LEIDEN (NL) | 1998-07-22 | — | — | EP | disclosed |
| EP-0655070-A1 | TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE | RIJKSUNIVERSITEIT LEIDEN (NL) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004545-A1 | TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE | RIJKSUNIVERSITEIT LEIDEN (NL) | 1994-03-03 | — | — | WO | disclosed |