Cyprazepam

SCHEMBL8350722

O=C(OCC(Cl)(Cl)Cl)OCC(Cl)(Cl)Cl.[O-][N+]1=C(c2ccccc2)c2cc(Cl)ccc2N=C(NCC2CC2)C1

nearest known ligand 0.53

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	1/20	0.53

▸	KDM4E	B2RXH2	1/20	0.47

▸	VCP	P55072	9/20	0.38

▸	CRHR1	P34998	1/20	0.34

▸	CHRM1	P11229	3/20	0.33

▸	CHRM3	P20309	2/20	0.32

▸	F11	P03951	2/20	0.32

▸	KLK1	P06870	1/20	0.32

▸	CHRM2	P08172	1/20	0.32

▸	CHRM4	P08173	1/20	0.32

▸	KLKB1	P03952	1/20	0.32

▸	PIM1	P11309	1/20	0.31

▸	STK4	Q13043	1/20	0.31

▸	STK3	Q13188	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Cyprazepam SCHEMBL30736035	0.89	CYP1A2 (0.56)	CYP1A2KDM4EVCPCRHR1CHRM1
Cyprazepam SCHEMBL114194	0.89	CYP1A2 (0.56)	CYP1A2KDM4EVCPCRHR1CHRM1
Cyprazepam SCHEMBL29040984	0.88	CYP1A2 (0.56)	CYP1A2KDM4EVCPCRHR1CHRM1
SCHEMBL28910535	0.78	CYP1A2 (0.59)	CYP1A2KDM4E
Hydrochloric Acid SCHEMBL11742135	0.75	CYP1A2 (0.56)	CYP1A2KDM4E
SCHEMBL7308839	0.75	CYP1A2 (0.56)	CYP1A2KDM4E
Chlordiazepoxide SCHEMBL3179106	0.75	CYP1A2 (0.64)	CYP1A2KDM4E
Chlordiazepoxide SCHEMBL7052471	0.75	CYP1A2 (0.61)	CYP1A2KDM4E
SCHEMBL11707387	0.74	CYP1A2 (0.61)	CYP1A2KDM4E
Chlordiazepoxide SCHEMBL3087365	0.74	CYP1A2 (0.63)	CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999030690-A1	ORAL DELIVERY FORMULATION	AXIA THERAPEUTICS, INC. (US)	1999-06-24	—	—	WO	disclosed