Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | DHPS | P49366 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3566918 | 0.81 | HDAC1 (0.58) | HDAC1F10PIN1NPC1RAB9A | |
| SCHEMBL13556367 | 0.78 | HDAC3 (0.59) | HDAC1POLBMEN1KMT2ANPC1 | |
| SCHEMBL17149299 | 0.75 | HDAC1 (0.65) | HDAC1POLBF10MEN1KMT2A | |
| SCHEMBL3569339 | 0.74 | HDAC1 (0.74) | HDAC1MEN1KMT2AMAPT | |
| SCHEMBL1886609 | 0.74 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL13556330 | 0.73 | CA12 (0.50) | HDAC1POLBHPGDF10MEN1 | |
| SCHEMBL14117943 | 0.73 | HDAC1 (0.55) | HDAC1POLBF10MEN1KMT2A | |
| SCHEMBL3575108 | 0.73 | HDAC1 (0.55) | HDAC1 | |
| SCHEMBL3562084 | 0.73 | HDAC1 (0.62) | HDAC1 | |
| SCHEMBL3568796 | 0.72 | HDAC1 (0.71) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058234-A2 | PHARMACEUTICAL COMBINATIONS OF PHTHALAZINE VEGF INHIBITORS AND BENZAMIDE HDAC INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-07-15 | — | — | WO | disclosed |