Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | MDM4 | O15151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401813 | 1.00 | IDO1 (0.53) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL29400614 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL30261869 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL30648981 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL872021 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL3722284 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL46349 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL29362906 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL29357117 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 | |
| SCHEMBL29460393 | 0.91 | MDM4 (0.55) | IDO1MDM2MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200407712-A1 | ARRAY-BASED CYCLIC PEPTIDE LIBRARIES | Cowper Sciences Inc. | 2020-12-31 | — | — | US | disclosed |
| EP-3749676-A1 | ARRAY-BASED CYCLIC PEPTIDE LIBRARIES | Healthtell Inc. (US) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019157362-A1 | ARRAY-BASED CYCLIC PEPTIDE LIBRARIES | HEALTHTELL INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| US-6008058-A | SYNTHESIZING AND SCREENING CYCLIC PEPTIDE LIBRARIES | UNIVERSITY OF LOUISVILLE (US) | 1999-12-28 | — | — | US | disclosed |