Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.39 |
| ▸ | ITGAL | P20701 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049100 | 0.86 | MEN1 (0.49) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL2162449 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL7462192 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL1746581 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL8339391 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL1473003 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL6677657 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL8781563 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL8336950 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A | |
| SCHEMBL28183039 | 0.85 | MEN1 (0.43) | MEN1KMT2AECE1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986074-A | CHELATE COMPOUNDS AS IMAGING AGENTS AND KITS | EMORY UNIVERSITY (US) | 1999-11-16 | — | — | US | disclosed |
| US-5955053-A | TECHNETIUM OR RHENIUM CHELATES WITH LIGANDS SUCH AS DITHIOUREA, CYSTEINYLETHYLENE OR THIOACETAMIDETHIOUREA FOR IMAGES | EMORY UNIVERSITY (US) | 1999-09-21 | — | — | US | disclosed |