Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219954 | 0.89 | GAA (0.65) | CHRM1TP53TDP1GAASMN1; SMN2 | |
| SCHEMBL12967015 | 0.85 | MAPK1 (0.70) | CHRM1TP53TDP1GAAMAPK1 | |
| SCHEMBL14810258 | 0.84 | CHRM1 (0.76) | CHRM1TP53TDP1GAAMAPK1 | |
| SCHEMBL14810985 | 0.84 | CHRM1 (0.76) | CHRM1TP53TDP1GAAMAPK1 | |
| SCHEMBL18849447 | 0.83 | GAA (0.57) | CHRM1TP53TDP1GAASMN1; SMN2 | |
| SCHEMBL4863171 | 0.83 | GAA (0.57) | CHRM1TP53TDP1GAASMN1; SMN2 | |
| SCHEMBL11178916 | 0.82 | CHRM1 (0.64) | CHRM1TP53TDP1GAAMAPK1 | |
| SCHEMBL8486938 | 0.82 | CHRM1 (0.64) | CHRM1TP53TDP1GAAMAPK1 | |
| SCHEMBL18114692 | 0.82 | TSHR (0.67) | CHRM1TP53TDP1GAAMAPK1 | |
| SCHEMBL8490717 | 0.81 | CHRM1 (0.56) | CHRM1TP53TDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032443-A1 | MUSCARINIC AGENTS AND USE THEREOF TO TREAT GLAUCOMA, MYOPIA, AND VARIOUS OTHER CONDITIONS | ALCON LABORATORIES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |