SCHEMBL8353088

SCHEMBL8353088

CCn1c(N2CCC[C@@H](N)C2)nc2cnn(Cc3cc(C)c4nc(C)c(C)nc4c3)c(=O)c21

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.52
CHRM1 P11229 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4066206 0.90 DPP4 (0.66) DPP4CHRM1
SCHEMBL4066210 0.90 DPP4 (0.66) DPP4CHRM1
SCHEMBL8353357 0.89 DPP4 (0.56) DPP4CHRM1
SCHEMBL13911722 0.82 DPP4 (0.57) DPP4CHRM1
SCHEMBL13485016 0.82 DPP4 (0.55) DPP4CHRM1
SCHEMBL8351880 0.82 DPP4 (0.55) DPP4CHRM1
SCHEMBL8351249 0.81 DPP4 (0.54) DPP4CHRM1
SCHEMBL8354316 0.81 DPP4 (0.54) DPP4CHRM1
SCHEMBL13911784 0.81 DPP4 (0.57) DPP4CHRM1
SCHEMBL8349842 0.80 DPP4 (0.63) DPP4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1569936-B1 NOVEL SUBSTITUTED IMIDAZO-PYRIDINONES AND IMIDAZO-PYRIDAZEIONES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA (DE) 2009-03-18 EP disclosed
WO-2004050658-A1 NOVEL SUBSTITUTED IMIDAZO-PYRIDINONES AND IMIDAZO-PYRIDAZEIONES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-06-17 WO disclosed