SCHEMBL8353141

SCHEMBL8353141

CCCCCCCCCCC(=O)OOc1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.47
CNR2 P34972 3/20 0.47
CYP2C9 P11712 1/20 0.45
POLM Q9NP87 1/20 0.45
POLK Q9UBT6 1/20 0.45
POLL Q9UGP5 1/20 0.45
POLH Q9Y253 1/20 0.45
TSHR P16473 1/20 0.44
HTR1B P28222 1/20 0.44
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PPARG P37231 2/20 0.43
PPARA Q07869 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28381119 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL28380496 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL28887199 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL32684916 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL32684946 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL2023424 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL29122753 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL3740934 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL8015856 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK
SCHEMBL451182 0.86 POLM (0.56) CNR1CNR2CYP2C9POLMPOLK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO disclosed