Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008408 | 0.94 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5005410 | 0.87 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5005441 | 0.86 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5010746 | 0.85 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5012010 | 0.85 | MAPK14 (0.55) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5007786 | 0.80 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5011970 | 0.79 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5010626 | 0.78 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL3307066 | 0.76 | GFER (0.46) | MAPK14MAPK13MAPK12MAPK11NTRK1 | |
| SCHEMBL5010659 | 0.75 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050651-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-17 | — | — | WO | disclosed |