Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356604 | 0.81 | PTGIR (0.60) | PTGIRPPARAPPARGPTGDR2FFAR1 | |
| SCHEMBL8358845 | 0.78 | PTGIR (0.65) | PTGIRPPARAPPARGPTGDR2PTGDR | |
| SCHEMBL8803458 | 0.78 | PPARA (0.57) | PTGIRPPARAPPARGPTGDR2MGLL | |
| SCHEMBL9813851 | 0.78 | PPARA (0.62) | PTGIRPPARAPPARGPTGDR2MGLL | |
| SCHEMBL8351589 | 0.78 | PTGIR (0.56) | PTGIRPPARAPPARGPTGDR2FFAR1 | |
| SCHEMBL8354916 | 0.78 | PTGIR (0.64) | PTGIRPPARAPPARGPTGDR2PTGDR | |
| SCHEMBL8804873 | 0.77 | PPARA (0.52) | PTGIRPPARAPPARGPTGDR2MGLL | |
| SCHEMBL8803787 | 0.77 | PTGIR (0.63) | PTGIRPPARAPPARGPTGDR2PTGDR | |
| SCHEMBL8358364 | 0.76 | PPARA (0.57) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL2769715 | 0.76 | PPARA (0.74) | PTGIRPPARAPPARGPTGDR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |