SCHEMBL8355186

SCHEMBL8355186

CC(=O)C(O)[C@H]1OC(Br)[C@@](O)(C(C)=O)[C@](O)(C(C)=O)[C@@]1(O)C(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9346141 1.00
SCHEMBL6705836 1.00
SCHEMBL7065528 1.00
SCHEMBL5902150 1.00
SCHEMBL2043596 1.00
SCHEMBL547054 1.00
SCHEMBL11103581 0.89
SCHEMBL9725008 0.88
SCHEMBL9475120 0.85
SCHEMBL9712160 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929538-A1 O?2 -ARYLATED OR O?2 -GLYCOSYLATED 1-SUBSTITUTED DIAZEN-1-IUM-1,2-DIOLATES AND O?2 -SUBSTITUTED 1- (2-CARBOXYLATO)PYRROLIDIN-1-YL]DIAZEN-1-IUM-1,2-DIOLATES THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-07-21 EP disclosed
WO-1998013358-A1 O2-ARYLATED OR O2-GLYCOSYLATED 1-SUBSTITUTED DIAZEN-1-IUM-1,2-DIOLATES AND O2-SUBSTITUTED 1-[(2-CARBOXYLATO)PYRROLIDIN-1-YL]DIAZEN-1-IUM-1,2-DIOLATES THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-04-02 WO disclosed
EP-0390783-A1 METHOD FOR IMPROVING THE FEED CONVERSION EFFICIENCY OF MEAT-PRODUCING ANIMALS BY ORAL ADMINISTRATION OF 2-DEOXY-D-HEXOSE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-10-10 EP disclosed
WO-1989002224-A1 METHOD FOR IMPROVING THE FEED CONVERSION EFFICIENCY OF MEAT-PRODUCING ANIMALS BY ORAL ADMINISTRATION OF 2-DEOXY-D-HEXOSE EASTMAN KODAK COMPANY (US) 1989-03-23 WO disclosed
EP-0142094-B1 METHOD FOR THE PREPARATION OF ACYLATED SUGARS CONTAINING AN ISOTHIOCYANATE RADICAL LINKED TO POSITION 1 OF THE GLYCOSE BAYER AG (DE) 1988-06-29 EP disclosed
US-4600771-A Process for the preparation of acylated sugars with a glycosidically bonded isothiocyanate group BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US disclosed
EP-0142094-A2 Method for the preparation of acylated sugars containing an isothiocyanate radical linked to position 1 of the glycose BAYER AG (DE) 1985-05-22 EP disclosed