Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442357 | 0.93 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| SCHEMBL3295002 | 0.93 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| Acetone SCHEMBL9580371 | 0.90 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| Acetic Acid SCHEMBL25434355 | 0.88 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| SCHEMBL9442609 | 0.86 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| SCHEMBL6420595 | 0.86 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| Butanone SCHEMBL28044177 | 0.86 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| Methyl Alcohol SCHEMBL28322454 | 0.85 | TSHR (0.57) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| SCHEMBL27615 | 0.85 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 | |
| SCHEMBL284717 | 0.85 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986124-A | Method for making compounds containing hydrocarbonoxysilyi groups by hydrosilylation using hydrido (hydrocarbonoxy) silane compounds | DOW CORNING ASIA, LTD. (JP) | 1999-11-16 | — | — | US | disclosed |