Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356470 | 0.87 | KDM4C (0.37) | KMT2AMEN1KDM4CDHFRNPC1 | |
| SCHEMBL8356945 | 0.85 | MEN1 (0.37) | KMT2AMEN1KDM4CNPC1RAB9A | |
| SCHEMBL8354600 | 0.80 | KDM4C (0.40) | KMT2AMEN1KDM4CDHFRNPC1 | |
| SCHEMBL8806002 | 0.74 | MEN1 (0.48) | KMT2AMEN1KDM4CDHFRNPC1 | |
| SCHEMBL8384076 | 0.74 | KDM4C (0.49) | KMT2AMEN1KDM4CDHFRNPC1 | |
| SCHEMBL3744988 | 0.73 | MEN1 (0.49) | KMT2AMEN1KDM4CDHFRNPC1 | |
| SCHEMBL8356468 | 0.73 | KDM4C (0.35) | KMT2AMEN1KDM4CNPC1RAB9A | |
| SCHEMBL10687441 | 0.72 | KDM4C (0.55) | KMT2AMEN1KDM4CDHFRNPC1 | |
| SCHEMBL14845812 | 0.71 | KDM4E (0.49) | KMT2AMEN1KDM4CDHFRNPC1 | |
| SCHEMBL3740904 | 0.71 | MEN1 (0.46) | KMT2AMEN1KDM4CDHFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |