Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PTGIR | P43119 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354916 | 0.89 | PTGIR (0.64) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL8358845 | 0.85 | PTGIR (0.65) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL8354868 | 0.84 | MEN1 (0.52) | MEN1KMT2APTGIRPPARAPPARG | |
| SCHEMBL8350671 | 0.80 | PTGIR (0.81) | MEN1KMT2APTGIRPPARAPPARG | |
| SCHEMBL8350669 | 0.80 | PTGIR (0.81) | MEN1KMT2APTGIRPPARAPPARG | |
| SCHEMBL8354759 | 0.80 | PPARA (0.51) | MEN1KMT2APPARAPPARGGAA | |
| SCHEMBL8350949 | 0.80 | PPARA (0.61) | MEN1KMT2APPARAPPARGALDH1A1 | |
| SCHEMBL8358844 | 0.79 | PPARA (0.47) | MEN1KMT2APTGIRPPARAPPARG | |
| SCHEMBL8356611 | 0.78 | PPARA (0.60) | MEN1KMT2APTGIRPPARAPPARG | |
| SCHEMBL8358622 | 0.78 | PPARA (0.59) | MEN1KMT2APPARAPPARGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |