Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | SULT1A1 | P50225 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361487 | 0.85 | APP (0.62) | MAOBMAPTHTTGAAL3MBTL1 | |
| SCHEMBL30370205 | 0.84 | EPHX2 (0.51) | MAOBMAPTGAAKDM4EMEN1 | |
| SCHEMBL29016615 | 0.84 | EPHX2 (0.44) | MAPTHTTALDH1A1APPEPHX2 | |
| SCHEMBL30370207 | 0.84 | EPHX2 (0.44) | MAPTHTTALDH1A1APPEPHX2 | |
| SCHEMBL29016598 | 0.84 | EPHX2 (0.51) | MAOBMAPTGAAKDM4EMEN1 | |
| SCHEMBL29016622 | 0.82 | SRD5A2 (0.52) | MAPTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL30370488 | 0.82 | SRD5A2 (0.52) | MAPTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL8357712 | 0.82 | MAOB (0.56) | MAOBMAPTHTTGAAL3MBTL1 | |
| SCHEMBL8361584 | 0.81 | MAPT (0.57) | MAOBMAPTHTTGAAL3MBTL1 | |
| SCHEMBL28984539 | 0.81 | CSNK1D (0.56) | EPHX2SCN4ACSNK1DDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919807-A | ANTICHOLESTEROL AGENTS | DR. KARL THOMAE GMBH (DE) | 1999-07-06 | — | — | US | disclosed |
| EP-0824529-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035681-A1 | BENZOTHIAZOLES AND BENZOXAZOLES, AS WELL AS DRUGS CONTAINING THEM, THEIR USE AND METHODS OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-11-14 | — | — | WO | disclosed |