Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 1.00 |
| ▸ | PPARA | Q07869 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358250 | 1.00 | PTGIR (1.00) | PTGIRPPARAPPARGPTGDR2ALOX15 | |
| SCHEMBL8354931 | 0.93 | PTGIR (0.88) | PTGIRPPARAPPARGPTGDR2ALOX15 | |
| SCHEMBL8354932 | 0.93 | PTGIR (0.88) | PTGIRPPARAPPARGPTGDR2ALOX15 | |
| SCHEMBL8350669 | 0.90 | PTGIR (0.81) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL8350671 | 0.90 | PTGIR (0.81) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL8358238 | 0.88 | PTGIR (0.78) | PTGIRPPARAALOX15 | |
| SCHEMBL8358241 | 0.88 | PTGIR (0.78) | PTGIRPPARAALOX15 | |
| SCHEMBL8803081 | 0.85 | PTGIR (0.74) | PTGIRPPARAPPARGPTGDR2LMNA | |
| SCHEMBL8802335 | 0.83 | PTGIR (0.70) | PTGIRPPARAPPARGPTGDR2 | |
| SCHEMBL8802326 | 0.83 | PTGIR (0.70) | PTGIRPPARAPPARGPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | claimed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | claimed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| JP-6056744-A | — | — | None | — | — | JP | disclosed |
| US-5935985-A | Phenoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5703099-A | TREATMENT OF THROMBOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASES, GASTRIC ULCER OR HYPERTENSION | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0558062-B1 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5536736-A | CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5378716-A | Prostaglandin agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| JP-H0656744-A | PHENOXYACETIC ACID DERIVATIVE AND PHARMACEUTICAL CONTAINING THE DERIVATIVE AS ACTIVE COMPONENT | ONO PHARMACEUT CO LTD | 1994-03-01 | — | — | JP | disclosed |
| EP-0558062-A2 | Phenoxyacetic acid derivatives and pharmaceutical compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |