SCHEMBL8358288

SCHEMBL8358288

CCC(=O)NCF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6170894 0.78
SCHEMBL95875 0.75
SCHEMBL11841402 0.75 MEN1 (0.60)
SCHEMBL12799428 0.75 MEN1 (0.78)
SCHEMBL11333738 0.73
SCHEMBL11336046 0.73
SCHEMBL606521 0.73
SCHEMBL11333794 0.73
SCHEMBL606520 0.73
SCHEMBL2032452 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103502226-A Cycloalkenyl aryl derivatives for CETP inhibitors CHONG KUN DANG PHARM CORP 2014-01-08 CN claimed
EP-3275874-B1 FUSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2019-10-30 EP disclosed
EP-3275874-A1 FUSED HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2018-01-31 EP disclosed
CN-103502226-A Cycloalkenyl aryl derivatives for CETP inhibitors CHONG KUN DANG PHARM CORP 2014-01-08 CN disclosed
CN-1829689-A Phenylmethylamine derivatives ZERIA PHARM CO LTD (JP) 2006-09-06 CN disclosed
US-5990140-A 2-ALKYL OR CYCLOALKYL-4-PHENYL-2-OXAZOLINE DERIVATIVES; PESTICIDES; INSECTICIDES; MITICIDES; LARVICIDES; LOW DOSAGE BAYER AKTIENGESELLSCHAFT (DE) 1999-11-23 US disclosed
EP-0831704-A1 USE OF OXAZOLINES FOR COMBATTING ECTOPARASITES BAYER AG (DE) 1998-04-01 EP disclosed
WO-1996041534-A1 USE OF OXAZOLINES FOR COMBATTING ECTOPARASITES BAYER AKTIENGESELLSCHAFT (DE) 1996-12-27 WO disclosed