Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29290501 | 0.90 | ABCB1 (0.70) | TAAR1KDM4EATMABCB1ABCG2 | |
| SCHEMBL42400 | 0.88 | TAAR1 (1.00) | TAAR1MAOBAOC3 | |
| Hydrochloric Acid SCHEMBL10917318 | 0.87 | TAAR1 (0.96) | TAAR1MAOBAOC3 | |
| Ammonia Solution, Strong SCHEMBL28996261 | 0.87 | TAAR1 (0.96) | TAAR1MAOBAOC3 | |
| SCHEMBL210639 | 0.87 | ATM (1.00) | TAAR1KDM4EATMPOLBTSHR | |
| SCHEMBL29351641 | 0.87 | ATM (1.00) | TAAR1KDM4EATMPOLBTSHR | |
| Hydrochloric Acid SCHEMBL19950932 | 0.85 | TAAR1 (0.93) | TAAR1MAOBAOC3 | |
| Hydrochloric Acid SCHEMBL11814399 | 0.85 | TAAR1 (0.56) | TAAR1KDM4EATMMAOBABCB1 | |
| Iodide SCHEMBL10518637 | 0.85 | ATM (0.96) | TAAR1KDM4EATMPOLBTSHR | |
| Hydrochloric Acid SCHEMBL3745006 | 0.85 | ATM (0.96) | TAAR1KDM4EATMPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031506-A9 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | LILLY CO ELI (US) | 1999-09-16 | — | — | WO | disclosed |
| WO-1999031506-A1 | PARALLEL SOLUTION PHASE SYNTHESIS OF LACTAMS | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999031507-A1 | PEPTIDOMIMETIC TEMPLATE-BASED COMBINATORIAL LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |