Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 8/20 | 0.51 |
| ▸ | TMPRSS11D | O60235 | 11/20 | 0.51 |
| ▸ | F10 | P00742 | 6/20 | 0.51 |
| ▸ | PLG | P00747 | 6/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381408 | 0.92 | F2 (0.53) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8354790 | 0.91 | F2 (0.49) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL12847292 | 0.89 | F2 (0.58) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL12514178 | 0.86 | F2 (0.56) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8290835 | 0.85 | F2 (0.59) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL8331318 | 0.85 | TMPRSS11D (0.48) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL14198653 | 0.85 | F2 (0.55) | F2TMPRSS6TMPRSS11DF10PLG | |
| Acetic Acid SCHEMBL30541187 | 0.84 | F2 (0.55) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL12514177 | 0.84 | F2 (0.58) | F2TMPRSS6TMPRSS11DF10PLG | |
| SCHEMBL17366096 | 0.83 | F2 (0.57) | F2TMPRSS6TMPRSS11DF10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076457-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2003-09-18 | — | — | WO | disclosed |