Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 17/20 | 0.49 |
| ▸ | WNT1 | P04628 | 10/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748042 | 1.00 | DYRK1A (0.49) | DYRK1AWNT1NPC1RAB9AUSP30 | |
| SCHEMBL8354506 | 0.92 | NPC1 (0.49) | DYRK1AWNT1NPC1RAB9AUSP30 | |
| SCHEMBL8357624 | 0.92 | NPC1 (0.49) | DYRK1AWNT1NPC1RAB9AUSP30 | |
| SCHEMBL12713559 | 0.87 | DYRK1A (0.48) | DYRK1AWNT1NPC1RAB9AUSP30 | |
| SCHEMBL8357618 | 0.85 | NPC1 (0.69) | DYRK1AWNT1NPC1RAB9AUSP30 | |
| SCHEMBL14748055 | 0.85 | NPC1 (0.69) | DYRK1AWNT1NPC1RAB9AUSP30 | |
| SCHEMBL8358755 | 0.85 | DYRK1A (0.67) | DYRK1AWNT1 | |
| SCHEMBL8358760 | 0.85 | DYRK1A (0.67) | DYRK1AWNT1 | |
| SCHEMBL12583369 | 0.83 | DYRK1A (0.47) | DYRK1AWNT1NPC1RAB9A | |
| SCHEMBL12713661 | 0.82 | DYRK1A (0.53) | DYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305675-A1 | Indazoles, Benzothiazoles, and Benzoisothiazoles, and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2004029050-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2004-04-08 | — | — | WO | disclosed |