Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | PDE1A | P54750 | 1/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5916549 | 0.85 | KMT2A (0.44) | PDE5APDE1APDE1BPDE1CKMT2A | |
| SCHEMBL1513983 | 0.85 | PDE5A (0.60) | PDE5APDE1APDE1BPDE1CKMT2A | |
| SCHEMBL8358527 | 0.84 | PDE5A (0.53) | PDE5APDE1APDE1BPDE1CKMT2A | |
| SCHEMBL8358661 | 0.83 | PDE5A (0.53) | PDE5APDE1APDE1BPDE1C | |
| SCHEMBL8358659 | 0.81 | PDE5A (0.47) | PDE5APDE1APDE1BPDE1C | |
| SCHEMBL6288549 | 0.80 | PDE5A (0.54) | PDE5APDE1APDE1BPDE1C | |
| SCHEMBL5916399 | 0.79 | PDE5A (0.51) | PDE5APDE1APDE1BPDE1CKMT2A | |
| SCHEMBL5619914 | 0.77 | PDE5A (0.52) | PDE5APDE1APDE1BPDE1C | |
| SCHEMBL5916454 | 0.77 | PDE2A (0.56) | PDE5APDE1APDE1BPDE1C | |
| SCHEMBL19198635 | 0.77 | PDE5A (0.49) | PDE5APDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005291-A1 | HETERO-CYCLICALY SUBSTITUTED IMIDAZOTRIAZINES | BAYER HEALTHCARE AG (DE) | 2004-01-15 | — | — | WO | disclosed |