SCHEMBL8358677

SCHEMBL8358677

CC(O)OC(=O)c1ccc2c(c1)cc(C(=O)NC1CCN(C(C)C)CC1)n2Cc1cc(-c2ccc(Cl)s2)on1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.79
F2 P00734 2/20 0.76
KLK1 P06870 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1674979 0.95 F10 (0.80) F10F2KLK1
SCHEMBL1675018 0.94 F10 (0.82) F10F2KLK1
SCHEMBL1675260 0.92 F10 (0.75) F10F2KLK1
SCHEMBL1675043 0.92 F10 (0.81) F10F2KLK1
SCHEMBL1674973 0.91 F10 (0.75) F10F2KLK1
SCHEMBL15927018 0.91 F10 (0.85) F10F2KLK1
SCHEMBL3240870 0.91 F10 (0.85) F10F2KLK1
Hydrochloric Acid SCHEMBL3236897 0.90 F10 (0.84) F10F2KLK1
SCHEMBL8359006 0.90 F10 (0.84) F10F2KLK1
SCHEMBL1675060 0.89 F10 (0.71) F10F2KLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003044014-A1 INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-05-30 WO disclosed