Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | XIAP | P98170 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 6/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15255695 | 0.88 | XIAP (0.43) | ACEXIAPF10 | |
| SCHEMBL15255697 | 0.83 | ACE (0.44) | ACEXIAPF10F2 | |
| SCHEMBL13050539 | 0.82 | XIAP (0.37) | ACEXIAP | |
| SCHEMBL12895000 | 0.80 | XIAP (0.36) | XIAP | |
| SCHEMBL10792822 | 0.79 | XIAP (0.42) | ACEXIAPF10F2 | |
| SCHEMBL10792831 | 0.79 | XIAP (0.42) | ACEXIAPF10F2 | |
| SCHEMBL205500 | 0.78 | ACE (0.49) | ACEXIAPF10F2 | |
| SCHEMBL2707170 | 0.78 | ACE (0.49) | ACEXIAPF10F2 | |
| SCHEMBL10793023 | 0.78 | ACE (0.51) | ACEXIAP | |
| SCHEMBL10793019 | 0.78 | ACE (0.51) | ACEXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509330-B2 | Angiotensin converting enzyme (ACE); neutral endopeptidase (NEP); containing a dipeptide derived from an amino acid, or a conformationally restricted dipeptide mimic | BRISTOL-MYERS SQUIBB COMPANY | 2003-01-21 | — | — | US | disclosed |