Acetic Acid

Acetic Acid

SCHEMBL8358969

CC(=O)O.O=C(O)O.O=CO

nearest known ligand 0.58

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.58
LCK P06239 1/20 0.58
FYN P06241 1/20 0.58
CA1 P00915 3/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
LMNA P02545 3/20 0.39
TSHR P16473 3/20 0.36
THPO P40225 1/20 0.36
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
TP53 P04637 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
EGLN3 Q9H6Z9 1/20 0.31
SLC15A2 Q16348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL6905387 0.96 FFAR3 (0.64) FFAR3LCKFYNCA1CA2
Acetic Acid SCHEMBL28907430 0.96
Acetic Acid SCHEMBL10680248 0.96 FFAR3 (0.64) FFAR3LCKFYNCA1CA2
Acetic Acid SCHEMBL27652008 0.96 FFAR3 (0.64) FFAR3LCKFYNCA1CA2
Acetic Acid SCHEMBL393952 0.96
Acetic Acid SCHEMBL6852066 0.92
Acetic Acid SCHEMBL8159122 0.92
Acetic Acid SCHEMBL9398214 0.92
Acetic Acid SCHEMBL28412946 0.92
Acetic Acid SCHEMBL6658761 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999030688-A1 METHODS OF LYOPHILIZING SOLUTIONS AUFFRET ANTHONY (GB) 1999-06-24 WO disclosed
US-5908962-A BY DIRECTLY INJECTING AMMONIA INTO A RECYCLE STREAM ORGANIC ACIDS ARE EFFICIENTLY NEUTRALIZED. GENERAL ELECTRIC COMPANY AND ILLA INTERNATIONAL (US) 1999-06-01 US disclosed
US-5767322-A WATER-ALKALINE EMULSION PROCESS USING A CASCADE OF REACTORS; USING AMMONIUM SODIUM CARBONATE AS A FIRST NEUTRALIZATION AGENT FOR ACIDIC BY-PRODUCTS AND SODIUM CARBONATE AS THE SECOND GENERAL ELECTRIC COMPANY (US) 1998-06-16 US disclosed