Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PYGM | P11217 | 9/20 | 0.48 |
| ▸ | PYGL | P06737 | 8/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646863 | 0.88 | POLB (0.49) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL15069734 | 0.82 | POLB (0.49) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL15069733 | 0.82 | POLB (0.49) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL28634306 | 0.82 | POLB (0.61) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL29664286 | 0.82 | POLB (0.65) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL7969637 | 0.82 | POLB (0.65) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL16210182 | 0.80 | POLB (0.42) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL28650646 | 0.80 | POLB (0.63) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL3073043 | 0.79 | POLB (0.62) | POLBKDM4EPYGMPYGLALDH1A1 | |
| SCHEMBL11406209 | 0.79 | CYP3A4 (0.50) | ARALDH1A1PPARDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962608-A | LIQUID PHASE; HYDROLYSIS OF AN ORGANOMETALLIC COMPOUND | RELIANCE ELECTRIC INDUSTRIAL CO. (US) | 1999-10-05 | — | — | US | disclosed |
| US-5939497-A | CLEAR THERMOPLASTIC RESIN COMPOSITIONS INCLUDE A POLYETHERIMIDE RESIN, A FIRST POLYESTER RESIN AND A SECOND POLYESTER RESIN, EXHIBIT RESISTANCE TO ELEVATED TEMPERATURE AND IMPROVED IMPACT PROPERTIES | GENERAL ELECTRIC COMPANY (US) | 1999-08-17 | — | — | US | disclosed |